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Evaluating Gencaro as a genetically-targeted treatment for atrial fibrillation (AF) in patients with heart failure and HFrEF
February 26, 2018
By: Betsy Louda
ARCA Biopharma announced clinical results from GENETIC-AF, a Phase 2B, double-blind, superiority clinical trial evaluating Gencaro (bucindolol hydrochloride) as a genetically-targeted treatment for atrial fibrillation (AF) in patients with heart failure and reduced left ventricular ejection fraction (HFrEF). In all patients, Gencaro demonstrated a similar treatment benefit compared to the active control, metoprolol succinate (TOPROL-XL). In U.S. patients (127 of 267 total patients), a...
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